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NewsJanuary 2015 Great start to the new year as PLOS Pathogens accepts paper titled "Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo". [ ABSTRACT ] [ FULL TEXT ] August 2014 BBSRC awards a three year grant to study adenovirus and coagulation factor interactions and the impact on virus stability and utility for gene therapy. August 2014 John is appointed Cardiovascular & Cancer Research Group Leader. July 2014 Paper demonstrating supra-physiological expression of Factor VIII is published in Molecular Therapy. [ ABSTRACT ] November 2013 Congratulations to Daxin Chen on his paper being published in Thrombosis Research. [ ABSTRACT ] July 2013 John is appointed Professor of Cardiovascular Biology at the University of Surrey. January 2012 Congratulations to Daxin Chen on his paper being published in Arteriosclerosis, Thrombosis, and Vascular Biology. [ ABSTRACT ] [ FULL TEXT ] September 2011 The Group leaves the Thrombosis Research Institute. John sets up Coagulare Biomedica Ltd and starts offering a consultancy service. He is appointed visiting Professor at King's College London, and is made a Fellow of the Royal College of Pathologists. August 2011 Congratulations to Ahad Rahim on his paper on the efficient delivery of genetic material to the fetal brain being accepted for publication in Gene Therapy. [ ABSTRACT ] [ FULL TEXT ] August 2011 Congratulations to Margaret Duffy on her paper on a cluster of basic amino acids in the factor X serine protease domain that mediate surface interaction of the adenovirus/factor X complexes being accepted for publication in the Journal of Virology. [ ABSTRACT ] December 2010 The recommendations of the Working Group on Nomenclature of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis, which John chaired, for a standard system of nomenclature of genetic variants in haemostasis are accepted for publication in Journal of Thrombosis and Haemostasis. [ FULL TEXT ] December 2010 John's presentation at the Developments in Protein Interaction Analysis (DiPIA, Barcelona) meeting features in the 'Safer Delivery' section of the article on label-free technologies in Genetic Engineering & Biotechnology News. [ FULL TEXT ] November 2010 Natalie Ward's paper documenting the development of codon optimised factor VIII expression cassettes for use in gene therapy for haemophilia A is accepted for publication in Blood. [ ABSTRACT ] [ FULL TEXT ] [ SUPPLEMENTAL FIGURE ] June 2010 Raul Alba's paper documenting the retargeting capacity of adenovirus serotype 5 engineered to no longer bind coagulation factor X is accepted for publication in Blood. [ ABSTRACT ] June 2010 The coagulation factor database, CoagBase, goes live on the International Society of Thrombosis and Haemostasis web site. John McVey designed this database to provide a resource of information about each coagulation factor, including links to reference cDNA and protein sequences.  September 2009 Jenny Greig's paper on the influence of coagulation factor X on adenovirus serotype 35 and chimeric vectors of Ad5 and Ad35 transduction of liver was published in the October 2009 (volume 17, number 10) issue of Molecular Therapy and made the front cover! [ COVER ] [ ABSTRACT ] [ FULL TEXT ]  April 2009 Raul Alba's paper dissecting the role of the adenovirus hexon hypervariable regions on factor X binding and transduction of liver cells was published in the 30 July 2009 (volume 114, number 5) issue of Blood. The paper was selected for an 'inside blood' editorial comment by Eric Kremmer. [ ABSTRACT ] [ EDITORIAL COMMENT ] April 2009 The illustration, by Marie Dauenhaeimer, accompanying John McVey's 'inside blood' editorial comment on 'FVIIa gene delivery: potential treatment for hemophilia?' in the 16 April 2009 (volume 13, number 16) issue of Blood was selected for the front cover! [ COVER ] [ EDITORIAL COMMENT ]  |